I have a couple.
Jungleland is one. When the Big Man hits those first couple notes of his solo, it gives me a lump, because he's gone now.
It doesn't matter what I'm doing. When that solo starts, I just sit back and just listen. To me, it's a perfect piece of music.
Also, anything from Journey ~ Escape always takes back to my junior year in high school. Had a job stocking shelves, had a steady girl, had my first car. A good time in my life.
This one is very, very new. Thanks to Soot, I am now an official hardcore Shinedown fan. In the 2012 Project thread, Soot posted the title cut, Amaryllis, and also laid in a runner up, Through The Ghost.
I immediately liked Amaryllis, but thought Through The Ghost was ok, nothing more.
Now? I hear Through The Ghost and it actually stirs me up, down inside.
That song strikes a nerve, and I don't even know why!!!
Ah, the power of song.